BEYOND GLYCAN BARRIERS: NON-COGNATE LIGANDS AND PROTEIN MIMICRY APPROACHES TO ELICIT BROADLY NEUTRALIZING ANTIBODIES FOR HIV-1

Abstract Human immunodeficiency virus type 1 (HIV-1) vaccine immunogens capable of inducing broadly neutralizing antibodies (bNAbs) remain here obscure.HIV-1 evades immune responses through enormous diversity and hides its conserved vulnerable epitopes on the envelope glycoprotein (Env) by displaying an extensive immunodominant glycan shield.In eli

Hydrocephalus is a known complication following surgical resection of a cerebral hemisphere for refractory epilepsy, yet the pathological mechanism remains poorly understood.We present a case of refractory aseptic inflammatory hydrocephalus following cerebral read more hemispherectomy surgery for refractory epilepsy treated with a combination of ce